Our Research Sub-Committee
Meet the fantastic group of clinicians, researchers, and expert patients who review our grant applications, and learn more about how they help to decide where SRUK’s funding goes.
Our Research Sub-Committee is made up of professionals with a wealth of scientific and medical knowledge about scleroderma and Raynaud's phenomenon, and expert patients who have first-hand experience of the conditions. They have experience in clinical practice and have sat on other advisory committees. Their role is to ensure grant applications submitted to SRUK meet the remit of the charity and the individual grant call, and to review applications in light of peer review comments submitted by external professionals with expertise in the field. Recommendations from the Research Sub-Committee will be submitted to the Board of Trustees for ratification.
Richard Watts (Chair)
Richard Watts was a Consultant Rheumatologist at the Ipswich Hospital NHS Trust until 2020. He is an honorary professor at Norwich Medical School. He was Editor-in-Chief of Rheumatology between 2002-2008, and the founding Editor-in-Chief of Rheumatology Advances in Practice. He edits the 5th edition of the Oxford Textbook of Rheumatology. His current academic interests are the epidemiology, aetiopathogenesis and treatment of autoimmune rheumatic disease. He is a principal investigator for studies in the classification and diagnosis of vasculitis, the importance of patient education in the management of long-term rheumatic disease and the organisation of services for people with rheumatoid arthritis. He was chair of the Heberden Committee of the British Society of Rheumatology (BSR) and a Trustee of the BSR.
Chris Edwards
Professor Edwards is a Consultant Rheumatologist and Associate Director of the National Institute for Health Research (NIHR) Southampton Clinical Research Facility within the University Hospital Southampton NHS Foundation Trust. He has been an Investigator on a number of clinical trials of therapies for inflammatory rheumatic diseases and as Associate Director of the NIHR Clinical Research Facility is engaged with the running of a large translational research facility. Professor Edwards is Clinical Director of the Southampton Musculoskeletal Research Unit, a recognised EULAR centre of excellence. Through this work, Professor Edwards is an investigator for a number of stratified medicine trials to better understand the targeting of therapies for individuals. He has worked extensively with the General Practice Research Database to define the patient experience across the UK and is Chair of the EULAR education committee.
Allan Lawrie
Allan has a background in scientific research for cardiovascular disease. He is Professor of Translational Cardiopulmonary Science and British Heart Foundation Senior Research Fellow at the University of Sheffield. He leads multi-disciplinary teams of clinical, basic and computational scientists investigating the mechanisms of pulmonary vascular disease and biomarkers to aid the identification of new therapeutic targets and treatment for the benefit of patients with Pulmonary Hypertension and associated conditions, including scleroderma.
David Scott
David was appointed Consultant Rheumatologist at the Norfolk and Norwich University Hospital in February 1988 and Honorary Professor to Norwich Medical School, UEA in 1998. He “retired” from his NHS post in July 2011, and is now an honorary consultant. David is a former President of the British Society for Rheumatology. He has a long-standing interest in systemic vasculitis and the rarer connective tissue diseases, and has written and lectured extensively on the subjects. He was also a Trustee on the SRUK Board.
Edith Brown
Edith was diagnosed with scleroderma and Raynaud’s over 20 years ago and although living with scleroderma has certainly been challenging it has also given her the opportunity make a contribution to research. Over the years, she has been involved in many research projects both as a trial participant, and a member of steering committees and advisory boards.
“Since my diagnosis I have greatly appreciated the vital role SRUK has played in funding and sponsoring research which has contributed to a better understanding of the disease and promoted more effective treatments. I also know that SRUK has a commitment to involve patients in every aspects of their work. I am confident that the decision to include “patient voices” will make a valuable contribution to the work of the Research Sub Committee."
Kim Fligelstone
Kim has lived with Diffuse Systemic Sclerosis since 1988, with significant kidney/renal involvement in the earlier years and has been involved in clinical research trials/projects as a patient during this time. As a EULAR (European League against Rheumatology) patient research partner (PRP) she will add experiential knowledge, with the aim of improving the relevance, quality and validity to the research process. Kim also supports SRUK’s helpline therefore has an understanding of the SRUK community, and what research would best benefit them.
How We Fund Research
Our Grant Application Review Process
At SRUK, we are dedicated to funding high-quality and innovative research that advances our understanding of Scleroderma and Raynaud’s and improves outcomes for people living with the conditions. Our grant application review process is designed to ensure that we select the most promising projects for funding, which align to the core areas of our research strategy: precision medicine, early detection and diagnosis, understanding the causes of the conditions, and improving quality of life.
Here’s how it works:
1. Application Submission
We invite researchers to submit their grant applications to our annual grant call. We ask applicants to provide a scientific overview, a plain English summary, and to detail the anticipated impact and outcomes of the proposed research.
2. Initial Research Committee Meeting
Once applications are received, our research committee—comprising clinical experts, researchers, and individuals with lived experience—conducts an initial meeting. The group collaborates to evaluate each application, ensuring that multiple perspectives are considered.
3. Shortlisting Projects
Following the initial review, the committee shortlists a number of promising projects for further evaluation. These shortlisted projects demonstrate significant potential and innovation, and require further evaluation by external peer reviewers who are leading experts in the field.
4. External Peer Review
The shortlisted applications undergo external peer review. We engage a minimum of two independent experts in the relevant field for each project. These experts provide a comprehensive written assessment of the applications, offering insights into the scientific merit and feasibility of each proposal, and the likelihood to deliver impact for patients.
5. Decision Meeting
After receiving the peer reviews, the research committee convenes for a decision meeting. During this meeting, committee members discuss the peer review feedback and make recommendations regarding which applications should receive funding.
6. Final Decision by the Board of Trustees
The research committee's recommendations are then presented to our board of trustees. The board evaluates these recommendations in light of the strategic aims of the charity and makes the final funding decisions.
Conflict of Interest Policy
At SRUK, we are committed to ensuring a rigorous and fair review process that aligns with our mission to support groundbreaking medical research in the field of Scleroderma and Raynaud’s. An important part of this is ensuring that all applications for funding are reviewed fairly, and that members of the committee and external peer reviewers do not have conflicts of interest with applicants.
We consider a substantial conflict of interest to occur when a reviewer:
- Is a named party in the grant application, either as a principal investigator, co-applicant, collaborator, or head of department.
- Has a close friendship, personal or familial relationship with any of the named parties on the grant application.
- Is employed at the same research institute as the lead applicant or a co-applicant of the grant application.
- May benefit financially from the work.
- Is directly involved in the work the applicant proposes to carry out.
- Has a co-publication history with the applicants within the last five years.
If a conflict of interest arises, the committee member or peer reviewer cannot assess the application, and is removed or replaced for the assessment of the application in question.
For any questions regarding the application process, please feel free to contact the research team at [email protected]