Prescribed Drug Treatments

Sometimes natural and over-the-counter therapies are not enough and it is necessary to take prescription medications. You should tell your Dr and pharmacist about all natural and prescription medicines you are taking so that they can check for any conflicts.

It is safe to take the below prescription medications in combination with the natural therapies. By improving the circulation these will help to treat Raynaud's and treat and prevent digital ulcers. These will take up to three weeks to take full effect but do not need to be taken permanently if you don't want to. It is quite common for them to be taken only in winter each year however they are safe to be taken permanently.

You may have to try several until you find the one, which works best for you. Side effects may include headaches, dizziness, flushing or low blood pressure. To try and avoid side effects it is recommended to start on a lower dose for a few days and go up to the full dose gradually.

Losartan 25mg-100mg daily or other angiotensin II receptor antagonists

Diltiazem 60mg three times daily or other calcium channel blockers

Fluoxetine 20mg-40mg daily or other serotonin reuptake antagonists

Simvastatin 10mg-40mg daily at night should be considered in all patients with elevated cholesterol and sometimes in other cases as there is limited evidence it may help prevent digital ulcers.

Clopidogrel 75mg daily is only used for people with digital ulcers

The following treatments are used in cases where people have tried many different therapies yet still suffer with digital ulcers. They are only available in exceptional circumstances under the supervision of a specialist clinic:

Sildenafil 25mg three times a day

Bosentan 62.5mg to 125mg twice daily

Intravenous Therapy

If you have been diagnosed with scleroderma, you may be offered an infusion of Iloprost treatment usually yearly. This involves a five-day stay in hospital receiving the drug through a drip. This will help to treat Raynaud's and to prevent digital ulcers occurring. If you do get digital ulcers, which won't respond to other treatments, then you may need an extra Iloprost infusion. More on this can be found below.

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