For some cases of severe Raynaud's, approaches other than medications may be a treatment option:
Nerves called sympathetic nerves in your hands and feet control the opening and narrowing of blood vessels in your skin. Cutting these nerves interrupts their exaggerated response. Through small incisions in the affected hands or feet, a doctor strips away these tiny nerves around the blood vessels. This surgery (sympathectomy) may reduce the frequency and duration of attacks, but it's not always successful.
Doctors can inject chemicals such as local anesthetics or onabotulinumtoxin type A (Botox) to block sympathetic nerves in affected hands or feet. You may need to have the procedure repeated if symptoms return or persist.