Tuesday 11th December 2018

Do certain genes lead to vascular involvement in scleroderma?

Professor Chris Denton and his team have set out to uncover why some individuals with systemic sclerosis suffer from digital ulcers whereas others suffer from vascular complications. By assessing the gene variants involved, they have identified a group of genes that may be linked to cardiovascular disease.

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Wednesday 5th December 2018

Nailfold Capillaroscopy: A technique to enable earlier intervention

In 2010, SRUK awarded a grant to Professor Arianne Herrick and her team at the University of Manchester for research to be conducted on nailfold capillaroscopy, which provides rheumatologists with a non-invasive window into the circulation in the nailbeds of patients.

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Monday 3rd December 2018

A study into the relationship between Systemic Sclerosis and cancer

The relationship between systemic sclerosis (SSc) and cancer, an idea first presented in the 1950s, is currently being examined in an epidemiological study funded by SRUK and led by Dr John Pauling at the University of Bath.

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Friday 30th November 2018

Enhanced Liver Fibrosis Test: A new biomarker of fibrosis in systemic sclerosis

A multicentre study spread across Europe was recently conducted to evaluate how effective the Enhanced Liver Fibrosis (ELF) Test would be as a biomarker of fibrosis (scarring) in systemic sclerosis (SSc).This would aid the understanding of what drives fibrosis in individuals and thus enable the application of precision medicine for treatment strategies.

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Thursday 8th November 2018

Is gastroesophageal reflux contributing to lung scarring?

A research collaboration between the Royal Free and Royal Brompton hospitals, funded by Scleroderma and Raynaud’s UK (SRUK), is investigating if reflux from the stomach into the oesophagus plays a role in lung scarring in scleroderma patients.

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Tuesday 6th November 2018

Is there a link between Localised and Systemic Scleroderma?

Keloid morphea is a rare, and hence poorly understood, form of localised scleroderma that only affects the skin. A new study into the condition has the potential to make a huge beneficial impact on our community.

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Friday 2nd November 2018

Alternative Therapies: Do they help Raynaud’s?

Over the years, many people living with Raynaud’s have advocated for the use of Chinese acupuncture and Chinese acupressure, but do they actually help?

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Tuesday 30th October 2018

Tenascin-C: A potential driving factor of organ fibrosis

Fibrosis is often the fundamental reason of morbidity and mortality in systemic scleroderma, however there is no effective therapy to prevent this process. A new study has identified a protein that may trigger fibrosis.

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Wednesday 17th October 2018

Is there a better way to differentiate Primary and Secondary Raynaud’s?

A study from Japan has devised a test which researchers claim could prove whether a patient has primary or secondary Raynaud’s.

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Tuesday 25th September 2018

Detecting heart abnormalities earlier: SRUK funding has potential to save lives

SRUK have made a significant contribution in providing funding for this two-year pilot study, which is well underway. Initial results are promising, and the success of the study means that the implantable loop recorder can then be examined through a wider clinical study.

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