Treatment for systemic sclerosis will be tailored to your individual needs, depending on what type of scleroderma you have and how it is affecting your body.

Your treatment should also follow a clear plan that has been agreed between you and your doctor. This plan should reflect your goals and wishes as far as possible.

Holistic care

Because scleroderma is a rare condition, and treatment can be complex, your care should be managed by a specialist team. This team will ideally have people from different health professions, who can give you support and bring their skills to different aspects of your care.

Medications

While they’re not the entire answer, medicines might play an important role in your treatment. Many different medicines are used to manage scleroderma, so it helps to think about them in groups, based on what aspects of the condition they work on.

There are medicines that aim to:

  • regulate your immune system
  • ease skin symptoms
  • help with Raynaud’s and finger ulcers
  • protect your heart, lungs and kidneys
  • help with digestive problems
  • help with sexual problems

Everyone’s experience is different, but all medicines can have side effects. Your doctor will talk you through the risks and benefits. Your team is also there to adjust your medicines or manage side effects if they do happen.

Non-drug treatments

Non-drug treatments are also important. These can include physiotherapy, occupational therapy and in some cases surgery. There are treatments to improve the appearance of your skin, and ways to cover up problem areas with cosmetics if you want to.

Specialised treatments

Find more information on treatments for specific areas of the body on the pages below

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Organ involvement in systemic sclerosis

Find our more about how the organs may be affected
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Skin in systemic sclerosis

Patients with systemic sclerosis will develop some skin changes. However, the severity and the problems created by the changes will vary greatly between patients.

BSR guideline for systemic sclerosis

At the end of 2024, the British Society for Rheumatology, SRUK, professionals with expertise in SSc and people with lived experience of SSc, developed a guideline for the management of systemic sclerosis. This was an update of the 2015 guideline.

The guideline offers systematic and evidence-based recommendations to support UK clinicians in management of systemic sclerosis across the whole life course.

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Find out more about systemic sclerosis

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Effects of Scleroderma on the body

Learn about the different effects systemic sclerosis can have on your body
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Managing your scleroderma symptoms

Find out more about how to manage your scleroderma symptoms
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Drugs and medications

No drug has been developed that can stop the underlying process of scleroderma. But a variety of medications can help control scleroderma symptoms or help prevent complications.